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Treatment with metformin significantly reduced both LV dimensions and increased both LV fractional shortening and LV ejection fraction compared with the pacing group (B).

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Cochrane review compared the effect of metformin alone with placebo or no intervention and found only a few trials providing data for mortality and morbidity.

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Furthermore, addition of metformin to sulfonylureas in patients with secondary sulfonylurea failure is reasonable in view of their synergistic mechanisms of action.

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Comparative effects of phenformin, metformin and glibenclamide on metabolic rhythms in maturity-onset diabetics.

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Treatment with compound C inhibited the effects of metformin and AICAR (which was similar to that of metformin) on apoptosis in cardiomyocytes exposed to H 2O 2 (D).

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Ask your doctor how much alcohol is safe to drink while you are taking glyburide and metformin.

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Metformin may help restore regular menstrual cycles and improve metabolism, thus possibly leading to weight loss in women with PCOS.

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Type Two Diabetics (T2DM) on metformin or sulfonylurea were followed over ten years.

Glyburide and metformin are not used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may occur if high blood sugar is not treated).

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It is not known if metformin has any effect on weight in people who do not have diabetes.

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